Biochemistry

This textbook 'Biochemistry' has become one of the most preferred text books (in India and many other countries) for the students as well as teachers in medical, biological and other allied sciences. The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, 'Biochemistry' is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.New to This Edition The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.

Inhalt
SECTION ONE Chemical Constituents of Life 1 Biomolecules and the cell 2 Carbohydrates 3 Lipids 4 Proteins and amino acids 5 Nucleic acids and nucleotides 6 Enzymes 7 Vitamins SECTION TWO Physiological Biochemistry 8 Digestion and absorption 9 Plasma proteins 10 Hemoglobin and porphyrins 11 Biological oxidation SECTION THREE Metabolisms 12 Introduction to metabolism 13 Metabolism of carbohydrates 14 Metabolism of lipids 15 Metabolism of amino acids 16 Integration of metabolism 17 Metabolism of nucleotides 18 Mineral metabolism SECTION FOUR Clinical Biochemistry and Nutrition 19 Hormones 20 Organ function tests 21 Water, electrolyte and acid-base balance 22 Tissue proteins and body fluids 23 Nutrition SECTION FIVE Molecular Biology and Biotechnology 24 DNA-replication, recombination and repair 25 Transcription and translation 26 Regulation of gene expression 27 Recombinant DNA and biotechnology SECTION SIX Current Topics 28 Human genome project 29 Gene therapy 30 Bioinformatics 31 Metabolism of xenobiotics (detoxification) 32 Prostaglandins and related compounds 33 Biological membranes and transport 34 Free radicals and antioxidants 35 Environmental biochemistry 36 Insulin, glucose homeostasis, and diabetes mellitus 37 Cancer 38 Acquired immunodeficiency syndrome (AIDS) SECTION SEVEN Basics to Learn Biochemistry 39 Introduction to bioorganic chemistry 40 Overview of biophysical chemistry 41 Tools of biochemistry 42 Immunology 43 Genetics APPENDICES Answers to Self-assessment Exercises i Abbreviations used in this book ii Origins of important biochemical words iii Common confusables in biochemistry iv Practical biochemistry-principles v Clinical biochemistry laboratory vi Case studies with biochemical correlations INDEX

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