Industrial Biotechnology

Technologien und Anwendungen der "weißen" Biochemie diskutieren die Autoren dieses Bandes unter Berücksichtigung des wirtschaftlichen Potenzials jeder Methode und der Folgen für die Gesellschaft. Der eher allgemein gehaltene Text verschafft dem Neueinsteiger auch einen aufschlussreichen Einblick in viele Industriezweige.

Autorentext
Professor Wim Soetaert is a Professor of Biotechnology at the University of Ghent, Belgium. After being awarded his PhD in 1991, he started his career in industry as research director of large agro-industrial companies in Germany and France. He then moved to Ghent University in 2003 to become full professor at the Center of Expertise InBio.be. He is vice-chairman of the biocatalysis section within the European Federation of Biotechnology (ESAB). Prof. Soetaert is the founder and chairman of Ghent Bio-Energy Valley and the bio Base Europe Pilot Plant, an open innovation pilot plant for biobased products and processes. Professor Erick J. Vandamme is Emeritus Professor at the Laboratory of Industrial Microbiology and Biocatalysis, Ghent University, Belgium, where he received his MSc, PhD and DSc in molecular biology, fermentation science and industrial biotechnology, respectively. He held postdoctoral positions at Oxford University, UK, MIT, Cambridge, USA, and at the University of London, UK. Professor Vandamme has edited or c-edited 12 reference books, written over 400 papers, holds several patents, and serves on the editorial boards of a number of journals. He has been awarded three honorary doctorates, and is the recipient of national and international scientific awards. He is an Elected Fellow of the American Academy of Microbiology and of the Society for Industrial Microbiology, has served on the boards of several European microbiological societies and is a member of the Royal Flemish Academy of Belgium for Science and the Arts.

Klappentext
Industrial Biotechnology, also referred to as "White Biotechnology", is a green and clean technology based on renewable resources, with promising increased conversion efficiency and specificity, less waste generation, lower energy consumption and reduced greenhouse gas emission. Describing most of the topics on white biotechnology admitted to the 7th EU Framework Program as well as new industrial production processes aiming towards reaching the Kyoto objectives, this comprehensive textbook covers the enabling sciences and technologies, the application domains, as well as the economic potential and societal impact. From the contents: * History of industrial biotechnology * Use of renewable versus fossil resources * Systems microbial biotechnology * Metabolic engineering and modeling * Fermentation technologies * Directed evolution and production of of industrial enzymes * Nanobiotechnology * Downstreamprocessing * Chemicals and biopharmaceuticals * Food and feed * Paper and pulp * Fuels from biomass * Enviromental, economic and societal aspects This comprehensive text is primarily directed at readers with a general interest in Industrial Biotechnology. It is equally very suitable as an introductory handbook to students , scientists and academics as well as researchers and engineers now active in a wide range of industries, including the bulk, fine and petrochemical sector, biotechnology and pharmaceutical companies, the personal care sector, the food and feed industries, agriculture and biorefineries, the paper and pulp sector, energy and fuel production and many more.

Inhalt
Preface THE SCOPE AND IMPACT OF INDUSTRIAL BIOTECHNOLOGY HISTORY OF INDUSTRIAL BIOTECHNOLOGY Early History The Penicillin Story The Coming of the Cephalosporins The Waksman Era Strain Improvement Semi-Synthetic Antibiotics to Combat Resistant Microbes The Primary Metabolites The Shift from Antibiotics to Pharmacological Agents The Biopharmaceutical Revolution Recombinant Hosts Enzymes Bioconversions Vaccines Systems Microbiology INDUSTRIAL SYSTEMS BIOLOGY Introduction Industrial Biotechnology Market Drivers for Industrial Biotechnology Industrial Systems Biology Metabolic Models Reconstructed Metabolic Network Models Industrial Systems Biology Case Studies Conclusion and Future Perspectives FERMENTATION TECHNOLOGY Introduction Types of Fermentations Fermentation Process Fermentation Medium Design sterilization of Air and Fermentation Medium Environmental Factors Fermentation Kinetics Fermentation Equipment Recovery of Fermentation Products Concluding Remarks DIRECTED EVOLUTION OF INDUSTRIAL BIOCATALYSTS Introduction Strategies for Protein Design Assay Systems Examples Conclusions THE INDUSTRIAL PRODUCTION OF ENZYMES Introduction Enzyme Production Enzyme Improvement Large-Scale Enzyme Applications Conclusions APPLIED BIOCATALYSIS: AN OVERVIEW Introduction The Design of the Bioconversion System Bioreactors Rationalizing and Speeding Up the Development and Characterization of a Bioconversion Process Concluding Remarks NANOBIOTECHNOLOGY Setting the Stage Industrial Perspective Nanotechnology in Biology and Biochemistry Biomimicry Materials and Products Processes and Devices Outlook DOWNSTREAM PROCESSING IN INDUSTRIAL BIOTECHNOLOGY Introduction Separations in Industrial Biotechnology Examples of Downstream Processing of Different Product Groups INDUSTRIAL BIOTECHNOLOGY IN THE CHEMICAL AND PHARMACEUTICAL INDUSTRIES Introduction Biocatalytic Processes: Scientific and Technological Perspectives Biocatalytic Processes: Business and Commercial Perspective Safety, Health, and the Environmental Perspective Outlook INDUSTRIAL BIOTECHNOLOGY IN THE FOOD AND FEED SECTOR Introduction Food Applications Food and Feed Applications Feed Applications INDUSTRIAL BIOTECHNOLOGY IN THE PAPER AND PULP SECTOR Introduction Enzymes for the Pulp and Paper Industry Enzymes as Process Aids Enzymes for Product Design Biorefinery Concepts Conclusions BIOFUELS: PRODUCTION AND APPLICATIONS A Renewed Interest in Biofuels Present Conversion Pathways Biodiesel Production from Vegetable Oils and Fats Ethanol and ETBE Production The Need for New Developments Lignocellulosic Biomass Resources Production of Ethanol from Lignocellulosic Biomass Production of Biofuels Through the Thermochemical Pathway Biorefineries Biofuels and Sustainability Conclusion ENVIRONMENTAL AND ECONOMIC ASPECTS OF INDUSTRIAL BIOTECHNOLOGY Introduction Methodology Overall Results Conclusions SOCIETAL ISSUES IN INDUSTRIAL BIOTECHNOLOGY Introduction The Impact of Industrial Biotechnology Public Perceptions of Industrial Biotechnology Societal Issues in Industrial Biotechnology Conclusions and Discussions: A Joint Agenda for the Smooth Introduction of Acceptable Sustainable Industrial Biotechnology

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