Meningiomas

Joung H. Lee has assembled a masterful volume on the diagnosis, treatment, and outcome of meningiomas. It is complete in that it covers all aspects of this tumor; every location is discussed by acknowledged experts and every technique is described in detail. Basic biology forms an important and up-to-date part of the text. This book will serve as a reference for many years; in particular, Dr. Lee feels surgeons and future patients will benefit. There is little question that these aims will be fulfilled in this important tour de force. John A. Jane, Sr. , MD, PhD Charlottesville, VA, USA vii Preface In planning this book, I had three major goals. The first was to compile and disseminate all the advances and new information relating to meningiomas which became available in the last 15-20 years. In this time frame, there has been a significant increase in our understanding in regards to the meningioma pathologic classification, the natural history and basic science. Dramatic technological advancements have also been made in diagnostic and interventional radiology as well as in surgical and radiation treatments for meningiomas, such as incorporation of the following in the treatment armamentaria: endoscopy, various skull base techniques, computer-assisted surgery and radiosurgery. Additionally, new information regarding surgical outcome and patient selection for surgery are becoming available, all of which are resulting in a significant change in how neurosurgeons treat patients with meningiomas. The second goal for this book was to teach and stimulate the next generation of neurosurgeons.

Contains most up-to-date information in all matters related to meningiomas with the most thorough coverage on the subject Written by multiple contributors who are internationally recognized experts in their respective fields from Asia, USA and Europe Includes supplementary material: sn.pub/extras

Autorentext
Dr Joung H Lee is Director, Center for Neurofibromatosis and Benign Tumors, Brain Tumor Institute and Head, Section of Skull Base Surgery, Department of Neurosurgery at the Cleveland Clinic Foundation. He has published over 40 journal articles and guest-edited Neurosurgery Clinics of North America: Adjunct treatment modalities for skull base tumors. W.B. Saunders, October 2000.


Klappentext
Meningiomas contains the most up-to-date information currently available on this increasingly common type of brain tumour, with contributions from internationally recognized experts in their respective fields working towards the uniform vision of one world-renowned editor. As the reported incidences of meningiomas found among otherwise healthy patients has increased over the last few years, so too has our understanding of them, aided in particular by advances in imaging studies such as computer tomography and magnetic resonance testing. As a result, meningiomas as a disease entity, is continuing to rise in clinical importance throughout neurology, neurosurgery and primary care, particularly in geriatrics. Moreover, its socio-economic impact on society will further increase over the next few decades, as the aging population also increases, with people living longer and enjoying healthier lives than ever before. Publication of a fully comprehensive and updated textbook on this important subject of meningiomas is therefore critically needed now to incorporate all of the aforementioned advancements. Meningiomas is an authoritative title, summarising the entirety of the topic, aimed at neurosurgeons, neurologists and general medical libraries throughout the world.

Inhalt
I GENERAL INFORMATION: Historical Perspective.- Epidemiology.- Meninges: Embryology.- Pathology.- Natural history, growth rates, recurrence.- II DIAGNOSTIC CONSIDERATIONS: Diagnostic radiology I: CT, MRI, Angio.- Diagnostic radiology II: Nuclear med, MRS, PET.- Lesions mimicking meningiomas.- Interventional radiology: Angio, embolization.- Neuro-ophthalmological evaluations.- III BASIC SCIENCE: Meningioma tumorigenesis: Review of basic science.- Meningothelial meningiomas.- Meningiomas of the central neuraxis.- Future treatment modalities I: Targeting the NF-2 & Ras Pathways.- Future treatment modalities II: Gene Therapy in meningiomas.- IV MANAGEMENT: Management options and principles.- Surgery: General principles.- Surgical adjuncts I: Endoscopy in meningioma surgery.- Surgical adjuncts: Image guided/CAS.- Seizures associated with meningiomas.- V ADJUNCT TREATMENT MODALITIES: Recent advances in therapeutic radiation.- Conventional RT for meningiomas.- Gamma Knife Radiosurgery.- Linear Accelerator Radiosurgery.- Brachytheraphy.- Medical therapy.- VI SURGICAL OUTCOME IN MENINGIOMA SURGERY: The factors influencing outcome in meningioma surgery.- The influence of co-morbidity and age in meningioma surgery outcome.- The influence of the tumor location, size and preoperative neurological symptoms in meningioma surgery outcome.- VII PATIENT SELECTION FOR SURGERY: THE 'CLASS' ALGORITHM: 'CLASS' algorithmic scale for surgical decision making: Rationale and design.- Validity of the 'CLASS' algorithmic scale: A retrospective study.- Utility of the 'CLASS' algorithmic scale: A prospective study.- VIII MENINGIOMAS BY LOCATION: PRESENTATION, SPECIAL CONSIDERATIONS, SURGICAL TECHNIQUE, OUTCOME: Convexity.- Parasagittal.- Falcine.- Olfactory groove/Planum spenoidale.- Tuberculum sella.- Clinoidal.- OpticSheath: Aggressive.- Optic Sheath: Conservative.- Lateral and middle sphenoid wing.- Orbitosphenoid.- Cavernous sinus: Aggressive.- Cavernous sinus: Conservative.- Temporal bone.- Petroclival: Aggressive.- Petroclival: Conservative.- Petrous.- Clival/Foramen Magnum.- Cerebellar convexity.- Tentorial.- Torcular/transverse & sigmoid sinus.- Pineal.- Ventricular.- Jugular foramen.- Paranasal sinuses.- Pediatric.- NF2/multiple.- Spinal.- IX MISCELLANEOUS: Meningioma surgery: Personal philosophy.- Functional improvement in meningioma surgery.- The rationale for surgery in young patients with small meningiomas.- Dural reconstruction.- Cranial reconstruction.

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