The Hippocampus Book

The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

The Hippocampus Book arrives at just the right time to guide the next generation of 'hippocampal researchers'... it will remain on my desk for a long time to come.

Zusammenfassung
The hippocampus is one of a group of remarkable structures embedded within the medial temporal lobe of the brain. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists working on hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behaviour, and computational algorithms. Well-organised in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unravelling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

Inhalt
1. Introduction; 2. Historical Perspectives: Proposed Functions, Biological Characteristics and Neurobiological Models of the Hippocampus; 3. Hippocampal Neuroanatomy; 4. Morphological Development of the Hippocampus; 5. Structure and Functional Properties of Hippocampal Neurons; 6. Synaptic Function; 7. Molecular Mechanisms of Synaptic Function in the Hippocampus: Neurotransmitter Exocytosis, Glutamatergic, GABAergic and Cholinergic Transmission; 8. Local Circuits; 9. Non-Synaptic Plasticity in the Hippocampus; 10. Synaptic Plasticity in the Hippocampus; 11. Hippocampal Neurophysiology in the Behaving Animal; 12. Functional Studies of the Human Hippocampus; 13. Theories of Hippocampal Function; 14. Computational Models of the Spatial and Mnemonic Functions of the Hippocampus; 15. Stress and the Hippocampus; 16. The Hippocampus and Human Disease

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