Alkaloids

Alkaloids are a large group of structurally complex natural products displaying a wide range of biological activities. The purpose of Alkaloids: A Treasury of Poisons and Medicines is to classify, for the first time, the alkaloids isolated from the natural sources until now. The book classifies all of the alkaloids by their biosynthetic origins. Of interest to the organic chemistry and medicinal chemistry communities involved in drug discovery and development, this book describes many alkaloids isolated from the medicinal plants, including those used in Japanese Kampo medicine.Classifies and lists alkaloids from natural sourcesOccurrence and biosynthetic pathways of alkaloidsIndicates key uses and bioactivity of alkaloids

Autorentext
Professor Shinji Funayama obtained his Ph.D. in natural product chemistry at Tohoku University (Sendai, Japan) in 1980. After three years as a postdoctoral fellow at the Department of Pharmacognosy and Pharmacology, College of Pharmacy, University of Illinois at Chicago (UIC) under the supervision of Professor Geoffrey A. Cordell, he joined the Kitasato Institute (Tokyo, Japan) as a senior researcher. After seven years, he joined as a Lecturer and was promoted to Assistant Professor at the Pharmaceutical Institute, Tohoku University. After six years in this position, he joined as an Associate Professor at Aomori University (Aomori, Japan). He was promoted to Professor there, and also served as a Guest Professor at Hirosaki University. After eight years, he became a Professor at Nihon Pharmaceutical University (Saitama, Japan) in 2003 and served as a Department Head for 10 years. He is the author of about 150 research publications, book chapters, comprehensive reviews, and professional publications; is the author of 11 books, with five more in progress; and is the Associate Editor-in-Chief of the Pharmaceutical Biology (USA). He is a Councilor of the Japanese Society for History of Pharmacy. His interests include the chemistry and biosynthesis of alkaloids, the relationship of poisons and human beings, the Japanese ancient history of Poisons and Medicines, and also the use of vegetables as chemical reagents.

Inhalt
1: Alkaloids Derived from Phenylalanine and Tyrosine 2: Alkaloids Derived from Tryptophan 3: Alkaloids Derived from Ornithine (Arginine) 4: Alkaloids Derived from Lysine 5: Alkaloids Derived from Proline 6: Alkaloids Derived from Glutamic Acid 7: Alkaloids Derived from Histidine 8: Alkaloids Derived from 2,3-Diaminopropionic Acid 9: Alkaloids Derived from Anthranilic Acid 10: Alkaloids Derived from Nicotinic Acid 11: Alkaloids Derived from Nucleic Acids and Related Compounds 12: Alkaloids Possessing the Porphine Skeleton 13: Alkaloids Derived from a m-C7N Unit 14: Alkaloids Derived from Terpenoids 15: Alkaloids Derived from Polyketides

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