Fmoc Solid Phase Peptide Synthesis

Zusatztext '..a completly fresh book.....a goldmine...' European Petide Society Klappentext In the years since the publication of Atherton and Sheppard's volume! the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The basic problems outstanding at the time of publication of this earlierwork have now been! for the most part! solved. As a result! innovators in the field have focussed their efforts to develop methodologies and chemistry for the synthesis of more complex structures. The focus of this new volume is much broader! and covers not only the essential procedures for theproduction of linear peptides but also more advanced techniques for preparing cyclic! side-chain modified! phospho- and glycopeptides. Many other methods also deserving attention have been included: convergent peptide synthesis; peptide-protein conjugation; chemoselective ligation; andchemoselective purification. The difficult preparation of cysteine and methionine-containing peptides is also covered! as well as methods for overcoming aggregation during peptide chain assembly and a survey of available automated instrumentation. Zusammenfassung Since the publication of Atherton and Sheppard's volume! the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The focus of this new volume is much broader! and covers the essential procedures.

'..a completly fresh book.....a goldmine...' European Petide Society

Klappentext
In the years since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The basic problems outstanding at the time of publication of this earlier
work have now been, for the most part, solved. As a result, innovators in the field have focussed their efforts to develop methodologies and chemistry for the synthesis of more complex structures. The focus of this new volume is much broader, and covers not only the essential procedures for the
production of linear peptides but also more advanced techniques for preparing cyclic, side-chain modified, phospho- and glycopeptides. Many other methods also deserving attention have been included: convergent peptide synthesis; peptide-protein conjugation; chemoselective ligation; and
chemoselective purification. The difficult preparation of cysteine and methionine-containing peptides is also covered, as well as methods for overcoming aggregation during peptide chain assembly and a survey of available automated instrumentation.

Inhalt
Preface; Introduction - a retrospective viewpoint; Basic Principles; Basic Procedures; Preparation and Handling of Peptides Containing Methionine and Cysteine; Difficult Peptides; Synthesis of Modified Peptides; Phosphopeptide Synthesis; Glycopeptide Synthesis; Convergent Peptide Synthesis; Methods of Preparing Peptide-carrier Conguates; Chemoselective and Orthogonal Ligation Techniques; Purification of Large Peptides Using Chemioselective Tags; Instrumentation for Automated Solid-Phase Peptide Synthesis; Manual Multiple Synthesis Methods; Appendix One; Appendix Two; Appendix Three; Index

#	Onlineshop	Preis CHF	Versand CHF	Total CHF
1	Seller	0.00	0.00	0.00