Cancer Immunotherapy

For some time immunotherapy has been heralded as a breakthrough approach for cancer treatment. Although the potential of this strategy remains solid, the approach needs considerable refinement. Whilst some programmes are looking to increase the understanding of molecular and cellular mechanisms underlying the stimulation of antitumor immunity, others are trying to find the most appropriate clinical setting that will reveal the role of the immune system in combating cancer. Among the most important discoveries have been tumor-specific antigens.

This thematic volume highlights some key issues and discusses where they may move forward. It has been put together by two leading cancer immunotherapists from two eminent institutions that focus on cancer research.

Zusammenfassung
Immunotherapy is heralded as a breakthrough approach for cancer treatment. Tumor-specific antigens are one of the important discoveries to find the most appropriate clinical setting to reveal the role of the immune system in combating cancer. This thematic volume highlights some key issues and discusses their direction.

Inhalt
Engineered cellular vaccines
Blockade of T cell checkpoints.
Serex in the identification of target antigens
New approaches to tumor immunotherapy
Melanoma antigens
Antibodies and chimeric molecules
Tumor Immunosurveillance
Dendritic Cells
Strategies for Tumor Vaccination
DNA vaccines

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